Please address any inquiries to:
Two Blades Foundation
1630 Chicago Avenue
Evanston, IL 60201
+1 847 425 1277
Science today published on-line a review on the progress and potential for deploying disease resistance in crop plants in a special issue on smarter pest control. The review focuses on the developments in the understanding of plant resistance mechanisms, the status of efforts to apply this knowledge to minimize crop losses, and new approaches to improving the ages-old practice of breeding for disease resistance.
June 25, 2013
2Blades announces that a second patent in 2Blades' TAL Code patent estate issued today. U.S. Pat. No. 8,470,973 is directed to methods of modifying genomes using TAL effector-endonucleases.
May 13, 2013
2Blades announces that the first TAL effector patent issued on April 16, 2013. U.S. Pat. No. 8,420,782, is directed to TAL effectors with endonuclease activity and is the first issuing patent of a comprehensive estate of patent applications.
April 9, 2013
Useful open resource for plant resistance genes:
April 3, 2013
2Blades is delighted to welcome Professor Sir David Baulcombe to our Scientific Advisory Board.
December 10, 2012
2Blades continues broad license access to its award-winning TAL technology through a non-exclusive license to Dupont Pioneer for uses in certain crops. Improvements to the technology will be granted back for 2Blades' humanitarian projects benefiting subsistence farming.
November 7, 2012
2Blades' TAL Code technology wins 2012 Agrow Award for Best Novel Agricultural Biotechnology.
Agrow Awards site
October 9, 2012
2Blades has signed a non-exclusive license with Mendel Biotechnology for the TAL code technology.
September 11, 2012
2Blades collaborator Prof. John Scott of the University of Florida presented trial results on transgenic disease-resistance in Florida tomato varieties last week at the annual Tomato Institute meeting. Scott presented the improved performance of parent and hybrid lines containing the pepper gene Bs2, as compared to the same lines without the gene and widely grown commercial varieties, in the presence of endemic bacterial spot infection. These results were highlighted in an interview in The Packer:
September 4, 2012
2Blades announces the expansion of rights to Monsanto under our non-exclusive license, announced in April, 2012, for broader access to the TAL Code technology. 2Blades will continue to receive a grant back of improvements to the technology for use in 2Blades’ humanitarian projects.
August 1, 2012
Results of tomato field trials demonstrating bacterial spot resistance and yield improvement were published today at PLOS ONE:
Transgenic resistance confers effective field level control of bacterial spot disease in tomato
July 9, 2012
2Blades announces the completion of a non-exclusive license with KWS for access to the TAL Code technology. KWS will grant improvements in the technology back to 2Blades for subsistence farming applications.
May 1, 2012
2Blades is pleased to announce completion of a non-exclusive license agreement with Bayer CropScience for the TAL code genome engineering technology. 2Blades will receive improvements to the TAL code for use in its subsistence farming applications.
April 16, 2012
Monsanto has completed a non-exclusive license with 2Blades for commercial uses of the TAL
Code technology in plants. Improvements to the technology will be granted back for 2Blades' humanitarian projects benefiting subsistence farming.
March 19, 2012
Services for TAL effector-based research tools were launched today by Life Technologies.
January 16, 2012
2Blades announces the signing of a non-exclusive license for the TAL Code technology to Syngenta for commercial uses in crop plants. Syngenta will grant 2Blades access to its improvements to the technology for use in 2Blades’ humanitarian efforts to support subsistence farming.
June 10, 2011
2Blades announces the licensing of the plant rights for the TAL Effector Code to Life Technologies for research tool applications. The exclusive license, made jointly with the technology inventors, will enable Life Technologies to develop research tools for all applications, as well as for commercial non-plant uses. 2Blades retains the rights for commercial applications in plants and green algae and intends to make licenses broadly available.
Press release from Life Technologies
August 1, 2010
2Blades is delighted to announce the addition of Jim Carrington to our Science Advisory Board.
March 15, 2010
New defenses deployed against plant diseases:
July 20, 2009
2Blades and The Sainsbury Laboratory partner to enhance the translation of fundamental discoveries in plant-pathogen interactions into practical applications in the field: