As part of our program to identify the diversity of resistance genes present in three important plant families, we have released the DNA sequences of a collection of disease resistance genes from 69 accessions of Arabidopsis thaliana (a plant in the cabbage family that is widely studied as a model system) and from 8 accessions in the Solanaceae (potato, tomato, and tobacco family).
These sequences were generated in the laboratories of Detlef Weigel (Max Planck Institute, Tübingen, Germany), Jeff Dangl (University of North Carolina), and Jonathan Jones (The Sainsbury Laboratory, Norwich, UK).
The open access datasets are now available for interrogation by the wider plant science community, and it is our hope that the data will shed light on important questions about the evolution of disease resistance in plants in response to ever-changing disease pressures, as well as helping researchers that are trying to understand the genetics of resistance to a particular disease.
Data can be accessed at www.2blades.org/resources.
This research is funded by the Gordon and Betty Moore Foundation through Grant GBMF4725 to Two Blades Foundation.